Volume 2, Issue 4 (October-November- December 2015)                   JNMS 2015, 2(4): 70-74 | Back to browse issues page

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Amirshahi M, Sanagoo A, Salehi A, Kerami A, Abdollahimohammad A, Mirshekari F, et al . Alobar holoprosencephaly: A case report. JNMS. 2015; 2 (4) :70-74
URL: http://jnms.mazums.ac.ir/article-1-163-en.html
Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran
Abstract:   (2309 Views)

Holoprosencephaly (HPE) is a rare congenital brain malformation associated with multiple midline facial defects. This anomaly is resulted from the failure of diverticulation and cleavage of primitive prosencephalon during weeks 4-8 of gestation. HPE is the most common forebrain developmental anomaly in human with the incidence rate of 0.49-1.2 cases per 10,000-20,000 term births. In this study, we described a case of HPE in a neonate with gestational age of 32 weeks. Antenatal ultrasonographic diagnosis was performed, and the infant was presented with macrocephaly, bilateral microphthalmia, hypotelorism, proboscis and ambiguous genitalia.

Full-Text [PDF 337 kb]   (1003 Downloads)    
Type of Study: Research | Subject: Nursing
Received: 2016/01/18 | Accepted: 2016/01/18 | Published: 2016/01/18

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