DOI: 10.18869/acadpub.jnms.2.4.70

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Amirshahi M, Sanagoo A, Salehi A, Kerami A, Abdollahimohammad A, Mirshekari F, et al . Alobar holoprosencephaly: A case report. JNMS. 2015; 2 (4) :70-74
Alobar holoprosencephaly: A case report. مجله علوم پرستاری و مامایی. 1394; 2 (4) :70-74


چکیده:   (747 مشاهده)

Holoprosencephaly (HPE) is a rare congenital brain malformation associated with multiple midline facial defects. This anomaly is resulted from the failure of diverticulation and cleavage of primitive prosencephalon during weeks 4-8 of gestation. HPE is the most common forebrain developmental anomaly in human with the incidence rate of 0.49-1.2 cases per 10,000-20,000 term births. In this study, we described a case of HPE in a neonate with gestational age of 32 weeks. Antenatal ultrasonographic diagnosis was performed, and the infant was presented with macrocephaly, bilateral microphthalmia, hypotelorism, proboscis and ambiguous genitalia.

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نوع مطالعه: پژوهشي | موضوع مقاله: پرستاری
دریافت: ۱۳۹۴/۱۰/۲۸ | پذیرش: ۱۳۹۴/۱۰/۲۸ | انتشار: ۱۳۹۴/۱۰/۲۸

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